LOCUS       KJ660346               18959 bp    cRNA    linear   VRL 18-DEC-2014
DEFINITION  Zaire ebolavirus isolate
            H.sapiens-wt/GIN/2014/Makona-Kissidougou-C15, complete genome.
ACCESSION   KJ660346
VERSION     KJ660346.2
KEYWORDS    .
SOURCE      Zaire ebolavirus
  ORGANISM  Zaire ebolavirus
            Viruses; Riboviria; Orthornavirae; Negarnaviricota;
            Haploviricotina; Monjiviricetes; Mononegavirales; Filoviridae;
            Ebolavirus.
REFERENCE   1  (bases 1 to 18959)
  AUTHORS   Baize,S., Pannetier,D., Oestereich,L., Rieger,T., Koivogui,L.,
            Magassouba,N., Soropogui,B., Sow,M.S., Keita,S., De Clerck,H.,
            Tiffany,A., Dominguez,G., Loua,M., Traore,A., Kolie,M.,
            Malano,E.R., Heleze,E., Bocquin,A., Mely,S., Raoul,H., Caro,V.,
            Cadar,D., Gabriel,M., Pahlmann,M., Tappe,D., Schmidt-Chanasit,J.,
            Impouma,B., Diallo,A.K., Formenty,P., Van Herp,M. and Gunther,S.
  TITLE     Emergence of Zaire Ebola virus disease in Guinea
  JOURNAL   N. Engl. J. Med. 371 (15), 1418-1425 (2014)
   PUBMED   24738640
REFERENCE   2  (bases 1 to 18959)
  AUTHORS   Rieger,T., Oestereich,L., Pahlmann,M., Cadar,D. and Gunther,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-APR-2014) Virology, Bernhard Nocht Institute for
            Tropical Medicine, WHO Collaborating Centre for Arbovirus and
            Haemorrhagic Fever Reference and Research, Bernhard-Nocht-Str. 74,
            Hamburg 20359, Germany
REFERENCE   3  (bases 1 to 18959)
  AUTHORS   Rieger,T., Oestereich,L., Pahlmann,M., Cadar,D. and Gunther,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-AUG-2014) Virology, Bernhard Nocht Institute for
            Tropical Medicine, WHO Collaborating Centre for Arbovirus and
            Haemorrhagic Fever Reference and Research, Bernhard-Nocht-Str. 74,
            Hamburg 20359, Germany
  REMARK    Sequence update by submitter
COMMENT     On Aug 26, 2014 this sequence version replaced KJ660346.1.
            
            ##Assembly-Data-START##
            Sequencing Technology :: Sanger dideoxy sequencing
            ##Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..18959
                     /organism="Zaire ebolavirus"
                     /mol_type="viral cRNA"
                     /isolate="H.sapiens-wt/GIN/2014/Makona-Kissidougou-C15"
                     /isolation_source="blood"
                     /host="Homo sapiens"
                     /db_xref="taxon:186538"
                     /country="Guinea"
                     /collection_date="2014"
     repeat_region   1..55
                     /note="putative leader region; regulation or initiation of
                     RNA replication"
                     /rpt_type=long_terminal_repeat
     primer_bind     1..24
                     /note="not an authentic part of this virus genome"
     gene            56..3026
                     /gene="NP"
     mRNA            56..3026
                     /gene="NP"
                     /product="nucleoprotein"
     regulatory      56..67
                     /regulatory_class="other"
                     /gene="NP"
                     /note="putative transcription start signal"
     CDS             470..2689
                     /gene="NP"
                     /note="encapsidation of genomic RNA"
                     /codon_start=1
                     /product="nucleoprotein"
                     /protein_id="AHX24646.1"
                     /translation="MDSRPQKVWMTPSLTESDMDYHKILTAGLSVQQGIVRQRVIPVY
                     QVNNLEEICQLIIQAFEAGVDFQESADSFLLMLCLHHAYQGDYKLFLESGAVKYLEGH
                     GFRFEVKKRDGVKRLEELLPAVSSGRNIKRTLAAMPEEETTEANAGQFLSFASLFLPK
                     LVVGEKACLEKVQRQIQVHAEQGLIQYPTAWQSVGHMMVIFRLMRTNFLIKFLLIHQG
                     MHMVAGHDANDAVISNSVAQARFSGLLIVKTVLDHILQKTERGVRLHPLARTAKVKNE
                     VNSFKAALSSLAKHGEYAPFARLLNLSGVNNLEHGLFPQLSAIALGVATAHGSTLAGV
                     NVGEQYQQLREAATEAEKQLQQYAESRELDHLGLDDQEKKILMNFHQKKNEISFQQTN
                     AMVTLRKERLAKLTEAITAASLPKTSGHYDDDDDIPFPGPINDDDNPGHQDDDPTDSQ
                     DTTIPDVVVDPDDGGYGEYQSYSENGMSAPDDLVLFDLDEDDEDTKPVPNRSTKGGQQ
                     KNSQKGQHTEGRQTQSTPTQNVTGPRRTIHHASAPLTDNDRRNEPSGSTSPRMLTPIN
                     EEADPLDDADDETSSLPPLESDDEEQDRDGTSNRTPTVAPPAPVYRDHSEKKELPQDE
                     QQDQDHIQEARNQDSDNTQPEHSFEEMYRHILRSQGPFDAVLYYHMMKDEPVVFSTSD
                     GKEYTYPDSLEEEYPPWLTEKEAMNDENRFVTLDGQQFYWPVMNHRNKFMAILQHHQ"
     regulatory      3015..3026
                     /regulatory_class="polyA_signal_sequence"
                     /gene="NP"
     gene            3032..4407
                     /gene="VP35"
     mRNA            3032..4407
                     /gene="VP35"
                     /product="VP35"
     regulatory      3032..3043
                     /regulatory_class="other"
                     /gene="VP35"
                     /note="putative transcription start signal"
     CDS             3129..4151
                     /gene="VP35"
                     /note="polymerase complex protein"
                     /codon_start=1
                     /product="VP35"
                     /protein_id="AHX24647.1"
                     /translation="MTTRTKGRGHTVATTQNDRMPGPELSGWISEQLMTGRIPVNDIF
                     CDIENNPGLCYASQMQQTKPNPKMRNSQTQTDPICNHSFEEVVQTLASLATVVQQQTI
                     ASESLEQRITSLENGLKPVYDMAKTISSLNRVCAEMVAKYDLLVMTTGRATATAAATE
                     AYWAEHGQPPPGPSLYEESAIRGKIESRDETVPQSVREAFNNLDSTTSLTEENFGKPD
                     ISAKDLRNIMYDHLPGFGTAFHQLVQVICKLGKDSNSLDIIHAEFQASLAEGDSPQCA
                     LIQITKRVPIFQDAAPPVIHIRSRGDIPRACQKSLRPVPPSPKIDRGWVCVFQLQDGK
                     TLGLKI"
     gene            4390..5894
                     /gene="VP40"
     mRNA            4390..5894
                     /gene="VP40"
                     /product="matrix protein"
     regulatory      4390..4401
                     /regulatory_class="other"
                     /gene="VP40"
                     /note="transcription start signal"
     regulatory      4397..4407
                     /regulatory_class="polyA_signal_sequence"
                     /gene="VP35"
     CDS             4479..5459
                     /gene="VP40"
                     /codon_start=1
                     /product="matrix protein"
                     /protein_id="AHX24648.1"
                     /translation="MRRVILPTAPPEYMEAIYPARSNSTIARGGNSNTGFLTPESVNG
                     DTPSNPLRPIADDTIDHASHTPGSVSSAFILEAMVNVISGPKVLMKQIPIWLPLGVAD
                     QKTYSFDSTTAAIMLASYTITHFGKATNPLVRVNRLGPGIPDHPLRLLRIGNQAFLQE
                     FVLPPVQLPQYFTFDLTALKLITQPLPAATWTDDTPTGSNGALRPGISFHPKLRPILL
                     PNKSGKKGNSADLTSPEKIQAIMTSLQDFKIVPIDPTKNIMGIEVPETLVHKLTGKKV
                     TSKNGQPIIPVLLPKYIGLDPVAPGDLTMVITQDCDTCHSPASLPAVVEK"
     regulatory      5883..5894
                     /regulatory_class="polyA_signal_sequence"
                     /gene="VP40"
     gene            5900..8305
                     /gene="GP"
     mRNA            5900..8305
                     /gene="GP"
                     /product="GP"
                     /note="unedited mRNA"
     regulatory      5900..5911
                     /regulatory_class="other"
                     /gene="GP"
                     /note="putative transcription start signal"
     CDS             join(6039..6923,6923..8068)
                     /gene="GP"
                     /ribosomal_slippage
                     /note="additional a residue inserted during transcription;
                     encodes two disulfide linked subunits GP1 and GP2;
                     receptor binding and fusion"
                     /codon_start=1
                     /product="virion spike glycoprotein precursor"
                     /protein_id="AHX24649.2"
                     /translation="MGVTGILQLPRDRFKRTSFFLWVIILFQRTFSIPLGVIHNSTLQ
                     VSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAG
                     EWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFF
                     LYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTI
                     RYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYASGKRSNTTGKLIWK
                     VNPEIDTTIGEWAFWETKKNLTRKIRSEELSFTAVSNGPKNISGQSPARTSSDPETNT
                     TNEDHKIMASENSSAMVQVHSQGRKAAVSHLTTLATISTSPQPPTTKTGPDNSTHNTP
                     VYKLDISEATQVGQHHRRADNDSTASDTPPATTAAGPLKAENTNTSKSADSLDLATTT
                     SPQNYSETAGNNNTHHQDTGEESASSGKLGLITNTIAGVAGLITGGRRTRREVIVNAQ
                     PKCNPNLHYWTTQDEGAAIGLAWIPYFGPAAEGIYTEGLMHNQDGLICGLRQLANETT
                     QALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPHDWTKNITDKID
                     QIIHDFVDKTLPDQGDNDNWWTGWRQWIPAGIGVTGVIIAVIALFCICKFVF"
     misc_feature    7526..7540
                     /gene="GP"
                     /note="precursor GP is cleaved by subtilisin-like cellular
                     protease furin into subunits GP1 and GP2 that are linked
                     by a disulfide bond; cleavage site"
     misc_feature    7790..7870
                     /gene="GP"
                     /note="immunosuppressive motif; other site"
     misc_feature    7985..8053
                     /gene="GP"
                     /note="transmembrane anchor; transmembrane region"
     CDS             6039..7133
                     /gene="GP"
                     /note="small non-structural secreted glycoprotein; sGP
                     secreted as an anti-parallel oriented homodimer"
                     /codon_start=1
                     /product="sGP"
                     /protein_id="AHX24650.1"
                     /translation="MGVTGILQLPRDRFKRTSFFLWVIILFQRTFSIPLGVIHNSTLQ
                     VSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAG
                     EWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFF
                     LYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTI
                     RYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYASGKRSNTTGKLIWK
                     VNPEIDTTIGEWAFWETKKTSLEKFAVKSCLSQLYQTDPKTSVVRVRRELLPTQRPTQ
                     QMKTTKSWLQKIPLQWFKCTVKEGKLQCRI"
     CDS             join(6039..6922,6924..6933)
                     /gene="GP"
                     /ribosomal_slippage
                     /note="second non-structural secreted glycoprotein;
                     secreted in a monomeric form; one a residue is deleted or
                     two additional a residues are inserted at the editing site
                     during transcription of the GP gene"
                     /codon_start=1
                     /product="ssGP"
                     /protein_id="AHX24651.1"
                     /translation="MGVTGILQLPRDRFKRTSFFLWVIILFQRTFSIPLGVIHNSTLQ
                     VSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSATKRWGFRSGVPPKVVNYEAG
                     EWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFF
                     LYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTI
                     RYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYASGKRSNTTGKLIWK
                     VNPEIDTTIGEWAFWETKKPH"
     misc_feature    6918..6924
                     /gene="GP"
                     /note="additional a residues are inserted or deleted
                     during transcription of the GP gene by the viral
                     polymerase"
     gene            8288..9740
                     /gene="VP30"
     mRNA            8288..9740
                     /gene="VP30"
                     /product="VP30"
     regulatory      8288..8299
                     /regulatory_class="other"
                     /gene="VP30"
                     /note="putative transcription start signal"
     regulatory      8295..8305
                     /regulatory_class="polyA_signal_sequence"
                     /gene="GP"
     CDS             8509..9375
                     /gene="VP30"
                     /note="minor nucleoprotein; polymerase complex protein"
                     /codon_start=1
                     /product="VP30"
                     /protein_id="AHX24652.1"
                     /translation="MEASYERGRPRAARQHSRDGHDHHVRARSSSRENYRGEYRQSRS
                     ASQVRVPTVFHKKRVEPLTVPPAPKDICPTLKKGFLCDSSFCKKDHQLESLTDRELLL
                     LIARKTCGSVEQQLNITAPKDSRLANPTADDFQQEEGPKITLLTLIKTAEHWARQDIR
                     TIEDSKLRALLTLCAVMTRKFSKSQLSLLCETHLRREGLGQDQAEPVLEVYQRLHSDK
                     GGSFEAALWQQWDRQSLIMFITAFLNIALQLPCESSAVVVSGLRTLVPQSDNEEASTN
                     PGTCSWSDEGTP"
     regulatory      9730..9740
                     /regulatory_class="polyA_signal_sequence"
                     /gene="VP30"
                     /note="putative"
     gene            9885..11518
                     /gene="VP24"
                     /note="putative"
     mRNA            9885..11496
                     /gene="VP24"
                     /product="VP24"
     regulatory      9885..9896
                     /regulatory_class="other"
                     /gene="VP24"
                     /note="transcription start signal"
     CDS             10345..11100
                     /gene="VP24"
                     /note="membrane-associated protein"
                     /codon_start=1
                     /product="VP24"
                     /protein_id="AHX24653.1"
                     /translation="MAKATGRYNLISPKKDLEKGVVLSDLCNFLVSQTIQGWKVYWAG
                     IEFDVTHKGMALLHRLKTNDFAPAWSMTRNLFPHLFQNPNSTIESPLWALRVILAAGI
                     QDQLIDQSLIEPLAGALGLISDWLLTTNTNHFNMRTQRVKEQLSLKMLSLIRSNILKF
                     INKLDALHVVNYNGLLSSIEIGTQNHTIIITRTNMGFLVELQEPDKSAMNRKKPGPAK
                     FSLLHESTLKAFTQGSSTRMQSLILEFNSSLAI"
     regulatory      11485..11496
                     /regulatory_class="polyA_signal_sequence"
                     /gene="VP24"
                     /note="putative"
     gene            11501..18282
                     /gene="L"
     mRNA            11501..18282
                     /gene="L"
                     /product="polymerase"
     regulatory      11501..11512
                     /regulatory_class="other"
                     /gene="L"
                     /note="transcription start signal"
     regulatory      11508..11518
                     /regulatory_class="polyA_signal_sequence"
                     /gene="VP24"
     CDS             11581..18219
                     /gene="L"
                     /note="polymerase; synthesis of viral RNAs;
                     transcriptional RNA editing"
                     /codon_start=1
                     /product="polymerase"
                     /protein_id="AHX24654.2"
                     /translation="MATQHTQYPDARLSSPIVLDQCDLVTRACGLYSSYSLNPQLRNC
                     KLPKHIYRLKYDVTVTKFLSDVPVATLPIDFIVPILLKALSGNGFCPVEPRCQQFLDE
                     IIKYTMQDALFLKYYLKNVGAQEDCVDDHFQEKILSSIQGNEFLHQMFFWYDLAILTR
                     RGRLNRGNSRSTWFVHDDLIDILGYGDYVFWKIPISLLPLNTQGIPHAAMDWYQTSVF
                     KEAVQGHTHIVSVSTADVLIMCKDLITCRFNTTLISKIAEVEDPVCSDYPNFKIVSML
                     YQSGDYLLSILGSDGYKIIKFLEPLCLAKIQLCSKYTERKGRFLTQMHLAVNHTLEEI
                     TEIRALKPSQAHKIREFHRTLIRLEMTPQQLCELFSIQKHWGHPVLHSETAIQKVKKH
                     ATVLKALRPIVIFETYCVFKYSIAKHYFDSQGSWYSVTSDRNLTPGLNSYIKRNQFPP
                     LPMIKELLWEFYHLDHPPLFSTKIISDLSIFIKDRATAVERTCWDAVFEPNVLGYNPP
                     HKFSTKRVPEQFLEQENFSIENVLSYAQKLEYLLPQYRNFSFSLKEKELNVGRTFGKL
                     PYPTRNVQTLCEALLADGLAKAFPSNMMVVTEREQKESLLHQASWHHTSDDFGEHATV
                     RGSSFVTDLEKYNLAFRYEFTAPFIEYCNRCYGVKNVFNWMHYTIPQCYMHVSDYYNP
                     PHNLTLENRNNPPEGPSSYRGHMGGIEGLQQKLWTSISCAQISLVEIKTGFKLRSAVM
                     GDNQCITVLSVFPLETDAGEQEQSAEDNAARVAASLAKVTSACGIFLKPDETFVHSGF
                     IYFGKKQYLNGVQLPQSLKTATRMAPLSDAIFDDLQGTLASIGTAFERSISETRHIFP
                     CRITAAFHTFFSVRILQYHHLGFNKGFDLGQLTLGKPLDFGTISLALAVPQVLGGLSF
                     LNPEKCFYRNLGDPVTSGLFQLKTYLRMIEMDDLFLPLIAKNPGNCTAIDFVLNPSGL
                     NVPGSQDLTSFLRQIVRRTITLSAKNKLINTLFHASADFEDEMVCKWLLSSTPVMSRF
                     AADIFSRTPSGKRLQILGYLEGTRTLLASKIINNNTETPVLDRLRKITLQRWSLWFSY
                     LDHCDNILAEALTQITCTVDLAQILREYSWAHILEGRPLIGATLPCMIEQFKVVWLKP
                     YEQCPQCSNAKQPGGKPFVSVAVKKHIVSAWPNASRISWTIGDGIPYIGSRTEDKIGQ
                     PAIKPKCPSAALREAIELASRLTWVTQGSSNSDLLIKPFLEARVNLSVQEILQMTPSH
                     YSGNIVHRYNDQYSPHSFMANRMSNSATRLIVSTNTLGEFSGGGQSARDSNIIFQNVI
                     NYAVALFDIKFRNTEATDIQYNRAHLHLTKCCTREVPAQYLTYTSTLDLDLTRYRENE
                     LIYDNNPLKGGLNCNISFDNPFFQGKQLNIIEDDLIRLPHLSGWELAKTIMQSIISDS
                     NNSSTDPISSGETRSFTTHFLTYPKIGLLYSFGAFVSYYLGNTILRTKKLTLDNFLYY
                     LTTQIHNLPHRSLRILKPTFKHASVMSRLMSIDPHFSIYIGGAAGDRGLSDAARLFLR
                     TSISSFLTFVKEWIINRGTIVPLWIVYPLEGQNPTPVNNFLHQIVELLVHDSSRHQAF
                     KTTINDHVHPHDNLVYTCKSTASNFFHASLAYWRSRHRNSNRKDLTRNSSTGSSTNNS
                     DGHIKRSQEQTTRDPHDGTERSLVLQMSHEIKRTTIPQENTHQGPSFQSFLSDSACGT
                     ANPKLNFDRSRHNVKSQDHNSASKREGHQIISHRLVLPFFTLSQGTRQLTSSNESQTQ
                     DEISKYLRQLRSVIDTTVYCRFTGIVSSMHYKLDEVLWEIENFKSAVTLAEGEGAGAL
                     LLIQKYQVKTLFFNTLATESSIESEIVSGMTTPRMLLPVMSKFHNDQIEIILNNSASQ
                     ITDITNPTWFKDQRARLPRQVEVITMDAETTENINRSKLYEAVHKLILHHVDPSVLKA
                     VVLKVFLSDTEGMLWLNDNLAPFFATGYLIKPITSSARSSEWYLCLTNFLSTTRKMPH
                     QNHLSCKQVILTALQLQIQRSPYWLSHLTQYADCDLHLSYIRLGFPSLEKVLYHRYNL
                     VDSKRGPLVSVTQHLAHLRAEIRELTNDYNQQRQSRTQTYHFIRTAKGRITKLVNDYL
                     KFFLIVQALKHNGTWQAEFKKLPELISVCNRFYHIRDCNCEERFLVQTLYLHRMQDSE
                     VKLIERLTGLLSLFPDGLYRFD"
     regulatory      18272..18282
                     /regulatory_class="polyA_signal_sequence"
                     /gene="L"
     repeat_region   18283..18959
                     /note="putative trailer region; regulation or initiation
                     of RNA replication"
                     /rpt_type=long_terminal_repeat
     primer_bind     18935..18959
                     /note="not an authentic part of this virus genome"
ORIGIN      
        1 cggacacaca aaaagaaaga agaattttta ggatcttttg tgtgcgaata actatgagga
       61 agattaataa ttttcctctc attgaaattt atatcggaat ttaaattgaa attgttactg
      121 taatcatacc tggtttgttt cagagccata tcaccaagat agagaacaac ctaggtctcc
      181 ggagggggca agggcatcag tgtgctcagt tgaaaatccc ttgtcaacat ctaggcctta
      241 tcacatcaca agttccgcct taaactctgc agggtgatcc aacaacctta atagcaacat
      301 tattgttaaa ggacagcatt agttcacagt caaacaagca agattgagaa ttaactttga
      361 ttttgaacct gaacacccag aggactggag actcaacaac cctaaagcct ggggtaaaac
      421 attagaaata gtttaaagac aaattgctcg gaatcacaaa attccgagta tggattctcg
      481 tcctcagaaa gtctggatga cgccgagtct cactgaatct gacatggatt accacaagat
      541 cttgacagca ggtctgtccg ttcaacaggg gattgttcgg caaagagtca tcccagtgta
      601 tcaagtaaac aatcttgagg aaatttgcca acttatcata caggcctttg aagctggtgt
      661 tgattttcaa gagagtgcgg acagtttcct tctcatgctt tgtcttcatc atgcgtacca
      721 aggagattac aaacttttct tggaaagtgg cgcagtcaag tatttggaag ggcacgggtt
      781 ccgttttgaa gtcaagaagc gtgatggagt gaagcgcctt gaggaattgc tgccagcagt
      841 atctagtggg agaaacatta agagaacact tgctgccatg ccggaagagg agacgactga
      901 agctaatgcc ggtcagttcc tctcctttgc aagtctattc cttccgaaat tggtagtagg
      961 agaaaaggct tgccttgaga aggttcaaag gcaaattcaa gtacatgcag agcaaggact
     1021 gatacaatat ccaacagctt ggcaatcagt aggacacatg atggtgattt tccgtttgat
     1081 gcgaacaaat tttttgatca aatttcttct aatacaccaa gggatgcaca tggttgccgg
     1141 acatgatgcc aacgatgctg tgatttcaaa ttcagtggct caagctcgtt tttcaggtct
     1201 attgattgtc aaaacagtac ttgatcatat cctacaaaag acagaacgag gagttcgtct
     1261 ccatcctctt gcaaggaccg ccaaggtaaa aaatgaggtg aactccttca aggctgcact
     1321 cagctccctg gccaagcatg gagagtatgc tcctttcgcc cgacttttga acctttctgg
     1381 agtaaataat cttgagcatg gtcttttccc tcaactgtcg gcaattgcac tcggagtcgc
     1441 cacagcccac gggagcaccc tcgcaggagt aaatgttgga gaacagtatc aacagctcag
     1501 agaggcagcc actgaggctg agaagcaact ccaacaatat gcggagtctc gtgaacttga
     1561 ccatcttgga cttgatgatc aggaaaagaa aattcttatg aacttccatc agaaaaagaa
     1621 cgaaatcagc ttccagcaaa caaacgcgat ggtaactcta agaaaagagc gcctggccaa
     1681 gctgacagaa gctatcactg ctgcatcact gcccaaaaca agtggacatt acgatgatga
     1741 tgacgacatt ccctttccag gacccatcaa tgatgacgac aatcctggcc atcaagatga
     1801 tgatccgact gactcacagg atacgaccat tcccgatgtg gtagttgatc ccgatgatgg
     1861 aggctacggc gaataccaaa gttactcgga aaacggcatg agtgcaccag atgacttggt
     1921 cctattcgat ctagacgagg acgacgagga caccaagcca gtgcctaaca gatcgaccaa
     1981 gggtggacaa cagaaaaaca gtcaaaaggg ccagcataca gagggcagac agacacaatc
     2041 cacgccaact caaaacgtca caggccctcg cagaacaatc caccatgcca gtgctccact
     2101 cacggacaat gacagaagaa acgaaccctc cggctcaacc agccctcgca tgctgacccc
     2161 aatcaacgaa gaggcagacc cactggacga tgccgacgac gagacgtcta gccttccgcc
     2221 cttagagtca gatgatgaag aacaggacag ggacggaact tctaaccgca cacccactgt
     2281 cgccccaccg gctcccgtat acagagatca ctccgaaaag aaagaactcc cgcaagatga
     2341 acaacaagat caggaccaca ttcaagaggc caggaaccaa gacagtgaca acacccagcc
     2401 agaacattct tttgaggaga tgtatcgcca cattctaaga tcacaggggc catttgatgc
     2461 cgttttgtat tatcatatga tgaaggatga gcctgtagtt ttcagtacca gtgatggtaa
     2521 agagtacacg tatccggact cccttgaaga ggaatatcca ccatggctca ctgaaaaaga
     2581 ggccatgaat gatgagaata gatttgttac actggatggt caacaatttt attggccagt
     2641 aatgaatcac aggaataaat tcatggcaat cctgcaacat catcagtgaa tgagcatgta
     2701 ataatgggat gatttaatcg acaaatagct aacattaaat agtcaaggaa cgcaaacagg
     2761 aagaattttt gatgtctaag gtgtgaatta ttatcacaat aaaagtgatt cttagttttg
     2821 aatttaaagc tagcttatta ttactagccg tttttcaaag ttcaatttga gtcttaatgc
     2881 aaataagcgt taagccacag ttatagccat aatggtaact caatatctta gccagcgatt
     2941 tatctaaatt aaattacatt atgcttttat aacttaccta ctagcctgcc caacatttac
     3001 acgatcgttt tataattaag aaaaaactaa tgatgaagat taaaaccttc atcatcctta
     3061 cgtcaattga attctctagc actagaagct tattgtcttc aatgtaaaag aaaagctggc
     3121 ctaacaagat gacaactaga acaaagggca ggggccatac tgtggccacg actcaaaacg
     3181 acagaatgcc aggccctgag ctttcgggct ggatctctga gcagctaatg accggaagga
     3241 ttcctgtaaa cgacatcttc tgtgatattg agaacaatcc aggattatgc tacgcatccc
     3301 aaatgcaaca aacgaagcca aacccgaaga tgcgcaacag tcaaacccaa acggacccaa
     3361 tttgcaatca tagttttgag gaggtagtac aaacattggc ttcattggct actgttgtgc
     3421 aacaacaaac catcgcatca gaatcattag aacaacgcat tacgagtctt gagaatggtc
     3481 taaagccagt ttatgatatg gcaaaaacaa tctcctcatt gaacagggtt tgtgctgaga
     3541 tggttgcaaa atatgatctt ctggtgatga caaccggtcg ggcaacagca accgctgcgg
     3601 caactgaggc ttattgggct gaacatggtc aaccaccacc tggaccatca ctttatgaag
     3661 aaagtgcgat tcggggtaag attgaatcta gagatgagac tgtccctcaa agtgttaggg
     3721 aggcattcaa caatctagac agtaccactt cactaactga ggaaaatttt gggaaacctg
     3781 acatttcggc aaaggatttg agaaacatta tgtatgatca cttgcctggt tttggaactg
     3841 ctttccacca attagtacaa gtgatttgta aattgggaaa agatagcaat tcattggaca
     3901 ttattcatgc tgagttccag gccagcctgg ctgaaggaga ctcccctcaa tgtgccctaa
     3961 ttcaaattac aaaaagagtt ccaatcttcc aagatgctgc tccacctgtc atccacatcc
     4021 gctctcgagg tgacattccc cgagcttgcc agaagagctt gcgtccagtc ccaccatcac
     4081 ccaagattga tcgaggttgg gtatgtgttt ttcagcttca agatggtaaa acacttggac
     4141 tcaaaatttg agccaatctc ttttccctcc gaaagaggca actaatagca gaggcttcaa
     4201 ctgctgaact atagggtatg ttacattaat gatacacttg tgagtatcag ccctagataa
     4261 tataagtcaa ttaaacaacc aagataaaat tgttcatatc ccgctagcag ctttaaagat
     4321 aaatgtaata ggagctatac ctctgacagt attataatta attgttatta agtaacccaa
     4381 accaaaaatg atgaagatta agaaaaacct acctcgactg agagagtgtt ttttcattaa
     4441 ccttcatctt gtaaacgttg agcaaaattg ttaaaaatat gaggcgggtt atattgccta
     4501 ctgctcctcc tgaatatatg gaggccatat accctgccag gtcaaattca acaattgcta
     4561 ggggtggcaa cagcaataca ggcttcctga caccggagtc agtcaatgga gacactccat
     4621 cgaatccact caggccaatt gctgatgaca ccatcgacca tgccagccac acaccaggca
     4681 gtgtgtcatc agcattcatc ctcgaagcta tggtgaatgt catatcgggc cccaaagtgc
     4741 taatgaagca aattccaatt tggcttcctc taggtgtcgc tgatcaaaag acctacagct
     4801 ttgactcaac tacggccgcc atcatgcttg cttcatatac tatcacccat ttcggcaagg
     4861 caaccaatcc gcttgtcaga gtcaatcggc tgggtcctgg aatcccggat caccccctca
     4921 ggctcctgcg aattggaaac caggctttcc tccaggagtt cgttcttcca ccagtccaac
     4981 taccccagta tttcaccttt gatttgacag cactcaaact gatcactcaa ccactgcctg
     5041 ctgcaacatg gaccgatgac actccaactg gatcaaatgg agcgttgcgt ccaggaattt
     5101 catttcatcc aaaacttcgc cccattcttt tacccaacaa aagtgggaag aaggggaaca
     5161 gtgccgatct aacatctccg gagaaaatcc aagcaataat gacttcactc caggacttta
     5221 agatcgttcc aattgatcca accaaaaata tcatgggtat cgaagtgcca gaaactctgg
     5281 tccacaagct gaccggtaag aaggtgactt ccaaaaatgg acaaccaatc atccctgttc
     5341 ttttgccaaa gtacattggg ttggacccgg tggctccagg agacctcacc atggtaatca
     5401 cacaggattg tgacacgtgt cattctcctg caagtcttcc agctgtggtt gagaagtaat
     5461 tgcaataatt gactcagatc cagttttaca gaatcttctc agggatagtg ataacatctt
     5521 tttaataatc cgtctactag aagagatact tctaattgat caatatacta aaggtgcttt
     5581 acaccattgt ctcttttctc tcctaaatgt agagcttaac aaaagactca taatatacct
     5641 gtttttaaaa gattgattga tgaaagatca tgactaataa cattacaaac aatcctacta
     5701 taatcaatac ggtgattcaa atgtcaatct ttctcattgc acatactctt tgtccttatc
     5761 ctcaaattgc ctacatgctt acatctgagg acagccagtg tgacttggat tggagatgtg
     5821 gaggaaaaat cggggcccat ttctaagttg ttcacaatct aagtacagac attgctcttc
     5881 taattaagaa aaaatcggcg atgaagatta agccgacagt gagcgtaatc ttcatctctc
     5941 ttagattatt tgtcttccag agtaggggtc atcaggtcct tttcaattgg ataaccaaaa
     6001 taagcttcac tagaaggata ttgtgaggcg acaacacaat gggtgttaca ggaatattgc
     6061 agttacctcg tgatcgattc aagaggacat cattctttct ttgggtaatt atccttttcc
     6121 aaagaacatt ttccatcccg cttggagtta tccacaatag tacattacag gttagtgatg
     6181 tcgacaaact agtttgtcgt gacaaactgt catccacaaa tcaattgaga tcagttggac
     6241 tgaatctcga ggggaatgga gtggcaactg acgtgccatc tgcgactaaa agatggggct
     6301 tcaggtccgg tgtcccacca aaggtggtca attatgaagc tggtgaatgg gctgaaaact
     6361 gctacaatct tgaaatcaaa aaacctgacg ggagtgagtg tctaccagca gcgccagacg
     6421 ggattcgggg cttcccccgg tgccggtatg tgcacaaagt atcaggaacg ggaccatgtg
     6481 ccggagactt tgccttccac aaagagggtg ctttcttcct gtatgatcga cttgcttcca
     6541 cagttatcta ccgaggaacg actttcgctg aaggtgtcgt tgcatttctg atactgcccc
     6601 aagctaagaa ggacttcttc agctcacacc ccttgagaga gccggtcaat gcaacggagg
     6661 acccgtcgag tggctattat tctaccacaa ttagatatca ggctaccggt tttggaacta
     6721 atgagacaga gtacttgttc gaggttgaca atttgaccta cgtccaactt gaatcaagat
     6781 tcacaccaca gtttctgctc cagctgaatg agacaatata tgcaagtggg aagaggagca
     6841 acaccacggg aaaactaatt tggaaggtca accccgaaat tgatacaaca atcggggagt
     6901 gggccttctg ggaaactaaa aaaacctcac tagaaaaatt cgcagtgaag agttgtcttt
     6961 cacagctgta tcaaacggac ccaaaaacat cagtggtcag agtccggcgc gaacttcttc
     7021 cgacccagag accaacacaa caaatgaaga ccacaaaatc atggcttcag aaaattcctc
     7081 tgcaatggtt caagtgcaca gtcaaggaag gaaagctgca gtgtcgcatc tgacaaccct
     7141 tgccacaatc tccacgagtc ctcaacctcc cacaaccaaa acaggtccgg acaacagcac
     7201 ccataataca cccgtgtata aacttgacat ctctgaggca actcaagttg gacaacatca
     7261 ccgtagagca gacaacgaca gcacagcctc cgacactccc cccgccacga ccgcagccgg
     7321 acccttaaaa gcagagaaca ccaacacgag taagagcgct gactccctgg acctcgccac
     7381 cacgacaagc ccccaaaact acagcgagac tgctggcaac aacaacactc atcaccaaga
     7441 taccggagaa gagagtgcca gcagcgggaa gctaggctta attaccaata ctattgctgg
     7501 agtagcagga ctgatcacag gcgggagaag gactcgaaga gaagtaattg tcaatgctca
     7561 acccaaatgc aaccccaatt tacattactg gactactcag gatgaaggtg ctgcaatcgg
     7621 attggcctgg ataccatatt tcgggccagc agccgaagga atttacacag aggggctaat
     7681 gcacaaccaa gatggtttaa tctgtgggtt gaggcagctg gccaacgaaa cgactcaagc
     7741 tctccaactg ttcctgagag ccacaactga gctgcgaacc ttttcaatcc tcaaccgtaa
     7801 ggcaattgac ttcctgctgc agcgatgggg tggcacatgc cacattttgg gaccggactg
     7861 ctgtatcgaa ccacatgatt ggaccaagaa cataacagac aaaattgatc agattattca
     7921 tgattttgtt gataaaaccc ttccggacca gggggacaat gacaattggt ggacaggatg
     7981 gagacaatgg ataccggcag gtattggagt tacaggtgtt ataattgcag ttatcgcttt
     8041 attctgtata tgcaaatttg tcttttagtc tttcttcaga ttgtttcacg gcaaaactca
     8101 acctcaaatc aatgaaacta ggatttaatt atatgaatca cttgaatcta agattacttg
     8161 acaaatgata acataataca ctggagcttc aaacatagcc aatgtgattc taactccttt
     8221 aaactcacag ttaatcataa acaaggtttg acatcaatct agctatatct ttaagaatga
     8281 taaacttgat gaagattaag aaaaaggtaa tctttcgatt atctttagtc ttcatccttg
     8341 attctacaat catgacagtt gtctttaatg aaaaaggaaa aaagcctttt tattaagttg
     8401 taataatcag atctgcaaac cggtagaatt tagttgtaac ctaacacaca caaagcattg
     8461 gtaaaaaagt caatagaaat ttaaacagtg agtgcagaca actcttaaat ggaagcttca
     8521 tatgagagag gacgcccccg agctgccaga cagcattcaa gggatggaca cgaccaccat
     8581 gttcgagcac gatcatcatc cagagagaat tatcgaggtg agtaccgtca atcaaggagc
     8641 gcctcacaag tgcgcgttcc tactgtattt cataagaaga gagttgaacc attaacagtt
     8701 cctccagcac ctaaagacat atgtccgacc ttgaaaaaag gatttttgtg tgacagtagt
     8761 ttttgcaaaa aagaccacca gttagaaagt ttaactgata gggaattact cctactaatc
     8821 gcccgtaaga cttgtggatc agtagaacaa caattaaata taactgcacc caaggactcg
     8881 cgcttagcaa atccaacggc tgatgatttc cagcaagagg aaggtccaaa aattaccttg
     8941 ttgacactga tcaagacggc agaacactgg gcgagacaag acatccgaac catagaggat
     9001 tccaaattaa gggcattgtt aactctatgt gctgtgatga cgaggaaatt ctcaaaatcc
     9061 cagctgagtc ttttgtgtga gacacaccta aggcgcgaag ggcttgggca agatcaggca
     9121 gaacccgttc tcgaagtata tcaacgatta cacagtgata aaggaggcag ttttgaagct
     9181 gcactatggc aacaatggga ccgacaatcc ctaattatgt ttatcactgc attcttgaat
     9241 atcgctctcc agttaccgtg tgaaagttct gctgtcgttg tttcagggtt aagaacattg
     9301 gttcctcaat cagataatga ggaagcttca accaacccgg ggacatgctc atggtctgat
     9361 gagggtaccc cttaataagg ctgactaaaa cactatataa ccttctactt gatcacaata
     9421 ctccgtatac ctatcatcat atatttaatc aagacgatat cctttaaaac ttattcagta
     9481 ctataatcac tctcatttca aattgataag atatgcataa ttgccttaat atataaagag
     9541 gtatgatata acccaaacat tgaccaaaga aaatcataat ctcgtatcgc tcgcaatata
     9601 acctgccaag catacctctt gcacaaagtg attcttgtac acaaataatg tttgactcta
     9661 caggaggtag caacgatcca tctcatcaaa aaataagtat tttatgattt actaatgatc
     9721 tcttaaaata ttaagaaaaa ctgacggaac ataaattctt tctgcttcaa gttgtggagg
     9781 aggtctatgg tattcgctat tgttatatta caatcaataa caagcttgta aaaatattgt
     9841 tcttgtttca ggaggtatat tgtgaccgga aaagctaaac taatgatgaa gattaatgcg
     9901 gaggtctgat gagaataaac cttattattc agattaggcc ccaagaggca ttcttcatct
     9961 ccttttagca aaatactatt tcaggatagt ccagctagtg acacgtcttt tagctgtata
    10021 ccagttgccc ctgagatacg ccacaaaagt gtctctgagc taaagtggtc tgtacacatc
    10081 tcatacattg tattaggggc aataatatct aattgaactt agccatttaa aatttagtgc
    10141 ataaatctgg gctaactcca ccaggtcaac tccattggct gaaaagaagc ccacctacaa
    10201 cgaacattac tttgagcgcc ctcacaatta aaaaataaga gcgtcgttcc aacaatcgag
    10261 cgcaaggtta caaggttgaa ctgagagtgt ctagacaaca aaatatcgat actccagaca
    10321 ccaagcaaga cctgagaaaa aaccatggcc aaagctacgg gacgatacaa tctaatatcg
    10381 cccaaaaagg acctggagaa aggggttgtc ttaagcgacc tctgtaactt cttagttagt
    10441 caaactattc aagggtggaa agtttattgg gctggtattg agtttgatgt gactcacaaa
    10501 ggaatggccc tattgcatag actgaaaact aatgactttg cccctgcatg gtcaatgaca
    10561 aggaacctat ttccccattt atttcaaaat ccgaattcca ctattgaatc accgctgtgg
    10621 gcactgagag tcatccttgc agcagggata caggaccagt taattgacca gtctttgatt
    10681 gaacccttag caggagccct tggtctgatc tctgattggc tgctaacaac caacactaac
    10741 catttcaaca tgcgaacaca acgtgtcaag gaacaattga gcctaaaaat gctgtcgttg
    10801 attcgatcca atattctcaa gtttattaac aaattggatg ctctacatgt cgtgaactac
    10861 aatggattat tgagcagtat tgaaattgga actcaaaatc atacaatcat cataactcga
    10921 actaacatgg gttttctggt ggagctccaa gaacccgaca aatcggcaat gaaccgcaag
    10981 aagcctgggc cggcgaaatt ttccctcctt catgagtcca cactgaaagc atttacacaa
    11041 gggtcctcga cacgaatgca aagtttaatt cttgaattca atagctctct tgctatctaa
    11101 ctaagatgga atacttcata ttgggctaac tcatatatgc tgactcaata gttaacttga
    11161 catctctgcc ttcataatca gatatataag cataataaat aaatactcat atttcttgat
    11221 aatttgttta accacagata aatcctcact gtaagccagc ttccaagttg acacccttac
    11281 aaaaaccagg actcagaatc cctcaaataa gagattccaa gacaacatca tagaattgct
    11341 ttattatatt aataagcatt ttatcactag aaatccaata tacgaaatgg ttaattgtaa
    11401 ctaaacccgc aggtcatgtg tgttaggttt cacaaattat atatattact aactccatac
    11461 tcgtaactaa cattagataa gtaggttaag aaaaaagctt gaggaagatt aagaaaaact
    11521 gcttattggg tctttccgtg ttttagatga agcagttgac attcttcctc ttgatattaa
    11581 atggctacac aacataccca atacccagac gccaggttat catcaccaat tgtattggac
    11641 caatgtgacc ttgtcactag agcttgcggg ttgtattcat catactccct taatccgcaa
    11701 ctacgcaact gtaaactccc gaaacatata taccgtttaa aatatgatgt aactgttacc
    11761 aagttcttaa gtgatgtacc agtggcgaca ttgcccatag atttcatagt cccaattctt
    11821 ctcaaggcac tatcaggcaa tgggttctgt cctgttgagc cgcggtgcca acagttctta
    11881 gatgaaatta ttaagtacac aatgcaagat gctctcttcc tgaaatatta tctcaaaaat
    11941 gtgggtgctc aagaagactg tgttgatgac cactttcaag aaaaaatctt atcttcaatt
    12001 cagggcaatg aatttttaca tcaaatgttt ttctggtatg acctggctat tttaactcga
    12061 aggggtagat taaatcgagg aaactctaga tcaacgtggt ttgttcatga tgatttaata
    12121 gacatcttag gctatgggga ctatgttttt tggaagatcc caatttcact gttaccactg
    12181 aacacacaag gaatccccca tgctgctatg gattggtatc agacatcagt attcaaagaa
    12241 gcggttcaag ggcatacaca cattgtttct gtttctactg ccgatgtctt gataatgtgc
    12301 aaagatttaa ttacatgtcg attcaacaca actctaatct caaaaatagc agaggttgag
    12361 gacccagttt gctctgatta tcccaatttt aagattgtgt ctatgcttta ccagagcgga
    12421 gattacttac tctccatatt agggtctgat gggtataaaa tcattaagtt tctcgaacca
    12481 ttgtgcttgg ctaaaattca attgtgctca aagtacaccg agaggaaggg ccgattctta
    12541 acacaaatgc atttagctgt aaatcacacc ctggaagaaa ttacagaaat acgtgcacta
    12601 aagccttcac aggctcacaa gatccgtgaa ttccatagaa cattgataag gctggagatg
    12661 acgccacaac aactttgtga gctattttcc atacaaaaac actgggggca tcctgtgcta
    12721 catagtgaaa cagcaatcca aaaagttaaa aaacatgcta cggtgctaaa agcattacgc
    12781 cctatcgtga ttttcgagac atattgtgtt tttaaatata gcattgcaaa acattatttt
    12841 gatagtcaag gatcttggta cagtgttacc tcagatagaa atctaacacc aggtcttaat
    12901 tcttatatca aaagaaatca attccctccg ttgccaatga ttaaagaact gctatgggaa
    12961 ttttaccacc ttgaccatcc tccacttttc tcaaccaaaa ttattagtga cttaagtatt
    13021 tttataaaag acagagctac tgcagtagaa aggacatgct gggatgcagt attcgagcct
    13081 aatgttctgg gatataatcc acctcacaaa ttcagtacca aacgtgtacc ggaacaattt
    13141 ttagagcaag aaaacttttc tattgagaat gttctttcct acgcgcaaaa actcgagtat
    13201 ctactaccac aatatcggaa tttttctttc tcattgaaag agaaagagtt gaatgtaggt
    13261 agaactttcg gaaaattgcc ttatccgact cgcaatgttc aaacactttg tgaagctctg
    13321 ttagctgatg gtcttgctaa agcatttcct agcaatatga tggtagttac ggaacgtgaa
    13381 caaaaagaaa gcttattgca tcaagcatca tggcaccaca caagtgatga tttcggtgag
    13441 catgccacag ttagagggag tagctttgta actgatttag agaaatacaa tcttgcattt
    13501 aggtatgagt ttacagcacc ttttatagaa tattgcaacc gttgctatgg tgttaagaat
    13561 gtttttaatt ggatgcatta tacaatccca cagtgttata tgcatgtcag tgattattat
    13621 aatccaccgc ataacctcac actggaaaat cgaaacaacc cccctgaagg gcctagttca
    13681 tacaggggtc atatgggagg gattgaagga ctgcaacaaa aactctggac aagtatttca
    13741 tgtgctcaaa tttctttagt tgaaattaag actggtttta agttgcgctc agctgtgatg
    13801 ggtgacaatc agtgcattac cgttttatca gtcttcccct tagagactga tgcaggcgag
    13861 caggaacaga gcgccgagga caatgcagcg agggtggccg ccagcctagc aaaagttaca
    13921 agtgcctgtg gaatcttttt aaaacctgat gaaacatttg tacattcagg ttttatctat
    13981 tttggaaaaa aacaatattt gaatggggtc caattgcctc agtcccttaa aacggctaca
    14041 agaatggcac cattgtctga tgcaattttt gatgatcttc aagggaccct ggctagtata
    14101 ggtactgctt ttgagcgatc catctctgag acacgacata tctttccttg cagaataacc
    14161 gcagctttcc atacgttctt ttcggtgaga atcttgcaat atcatcacct cggatttaat
    14221 aaaggttttg accttggaca gttaacactc ggcaaacctc tggatttcgg aacaatatca
    14281 ttggcactag cggtaccgca ggtgcttgga gggttatcct tcttgaatcc tgagaaatgt
    14341 ttctaccgga atctaggaga tccagttacc tcaggtttat tccagttaaa aacttatctc
    14401 cgaatgattg agatggatga tttattctta cctttaattg cgaagaaccc tgggaactgc
    14461 actgccattg actttgtgct aaatcctagc ggattaaatg ttcctgggtc gcaagactta
    14521 acttcatttc tgcgccagat tgtacgtagg actatcaccc taagtgcgaa aaacaaactt
    14581 attaatacct tatttcatgc atcagctgac ttcgaagacg aaatggtttg taagtggctc
    14641 ttatcatcaa ctcctgttat gagtcgtttc gcagccgata tattttcacg cacgccgagc
    14701 gggaagcgat tgcaaattct aggatacttg gaaggaacac gcacattatt agcctctaag
    14761 atcatcaaca ataatacaga gacgccggtt ttggacagac tgaggaagat aacattgcaa
    14821 aggtggagtc tatggtttag ttatcttgat cattgtgata atatcctggc ggaggcttta
    14881 acccaaataa cttgcacagt tgatttagca cagatcctga gggaatattc atgggcacat
    14941 attttagagg ggagacctct tattggagcc acactcccat gtatgattga gcaattcaaa
    15001 gtggtttggc tgaaacccta cgaacaatgt ccgcagtgtt caaatgccaa gcaacctggt
    15061 gggaaaccat tcgtgtcagt agcagtcaag aaacatattg ttagtgcatg gccaaatgca
    15121 tcccgaataa gctggactat cggggatgga atcccataca ttggatcaag gacagaagat
    15181 aagatagggc aacctgctat taaaccaaaa tgtccttccg cagccttaag agaggccatt
    15241 gaattggcgt cccgtttaac atgggtaact caaggcagtt cgaacagtga cttgctaata
    15301 aaaccatttt tggaagcacg agtaaattta agtgttcaag aaatacttca aatgacccct
    15361 tcacattact cgggaaatat tgttcatagg tacaacgatc aatacagtcc tcattctttc
    15421 atggccaatc gtatgagtaa ctcagcaacg cgattgattg tttctacaaa cactttaggt
    15481 gagttttcag gaggtggcca atcggcacgc gacagcaata ttattttcca gaatgttata
    15541 aattatgcag ttgcactgtt cgatattaaa tttagaaaca ctgaggctac agatatccag
    15601 tataatcgtg ctcaccttca tctaactaag tgttgcaccc gggaggtacc agctcagtac
    15661 ttaacataca catctacatt ggatttagat ttaacaagat accgagaaaa tgaattgatt
    15721 tatgacaata atcctctaaa aggaggactc aattgcaata tctcatttga taacccattt
    15781 ttccaaggca aacagctgaa cattatagaa gatgacctta ttcgactgcc tcacttatct
    15841 ggatgggagc tagctaagac catcatgcaa tcaattattt cagatagcaa taattcgtct
    15901 acagacccaa ttagcagtgg agaaacaaga tcattcacta cccatttctt aacttatccc
    15961 aagataggac ttctgtacag ttttggggcc tttgtaagtt attatcttgg caatacaatt
    16021 cttcggacta agaaattaac acttgacaat tttttatatt acttaactac ccaaattcat
    16081 aatctaccac atcgctcatt gcgaatactt aagccaacat tcaaacatgc aagcgttatg
    16141 tcacgattaa tgagtattga tccccatttt tctatttaca taggcggtgc tgcaggtgac
    16201 agaggactct cagatgcggc caggttattt ttgagaacgt ccatttcatc ttttcttaca
    16261 tttgtaaagg aatggataat taatcgcgga acaattgtcc ctttatggat agtatatcca
    16321 ttagagggtc aaaatccaac acctgttaat aatttcctcc atcagatcgt agaactgctg
    16381 gtgcatgatt catcaagaca ccaggctttt aaaactacca taaatgatca tgtacatcct
    16441 cacgacaatc ttgtttacac atgtaagagt acagccagca atttcttcca tgcgtcattg
    16501 gcgtactgga ggagcaggca cagaaacagc aaccgaaaag acttgacaag aaactcttca
    16561 actggatcaa gcacaaacaa cagtgatggt catattaaga gaagtcaaga acaaaccacc
    16621 agagatccac atgatggcac tgaacggagt ctagtcctgc aaatgagcca tgaaataaaa
    16681 agaacgacaa ttccacaaga gaacacgcac cagggtccgt cgttccagtc atttctaagt
    16741 gactctgctt gcggtacagc aaacccaaaa ctaaatttcg atagatcgag acacaatgtg
    16801 aaatctcagg atcataactc agcatccaag agggaaggtc atcaaataat ctcacatcgt
    16861 ctagtcctac ctttctttac attatctcaa gggacacgcc aattaacgtc atccaatgag
    16921 tcacaaaccc aagatgagat atcaaagtac ttacggcaat tgagatccgt cattgatacc
    16981 acagtttatt gtaggtttac cggtatagtc tcgtccatgc attacaaact tgatgaggtc
    17041 ctttgggaaa tagagaattt taagtcggct gtgacgctgg cagagggaga aggtgctggt
    17101 gccttactat tgattcagaa ataccaagtt aagaccttat ttttcaacac gctagctact
    17161 gagtccagta tagagtcaga aatagtatca ggaatgacta ctcctaggat gcttctacct
    17221 gttatgtcaa aattccataa tgaccaaatt gagattattc ttaacaactc agcaagccaa
    17281 ataacagaca taacaaatcc tacttggttt aaagaccaaa gagcaaggct acctaggcaa
    17341 gtcgaggtta taaccatgga tgcagagacg acagagaata taaacagatc gaaattgtac
    17401 gaagctgtac ataaattgat cttacaccat gttgatccca gcgtattgaa agcagtggtc
    17461 cttaaagtct ttctaagtga taccgagggt atgttatggc taaatgataa tctagccccg
    17521 ttttttgcca ctgggtattt aattaagcca ataacgtcaa gtgccaggtc tagtgagtgg
    17581 tatctttgtc tgacgaactt cttatcaact acacgtaaga tgccacacca aaaccatctc
    17641 agttgtaagc aggtaatact tacggcattg caactgcaaa ttcaacggag cccatactgg
    17701 ctaagtcatt taactcagta tgctgactgc gatttacatt taagctatat ccgccttggt
    17761 tttccatcat tagagaaagt actataccac aggtataacc ttgtcgattc aaaaagaggt
    17821 ccactagtct ctgtcactca gcacttagca catcttaggg cagagattcg agaattgacc
    17881 aatgattata atcaacagcg acaaagtcgg actcaaacat atcactttat tcgtactgca
    17941 aaaggacgaa tcacaaaact agtcaatgat tatttaaaat tctttcttat tgtacaagca
    18001 ttaaaacata atgggacatg gcaagctgag tttaagaaat taccagagtt gattagtgtg
    18061 tgcaataggt tctatcatat tagagattgt aattgtgaag aacgtttctt agttcaaacc
    18121 ttatatttac atagaatgca ggattctgaa gttaagctta tcgaaaggct gacagggctt
    18181 ctgagtttat ttccagatgg tctctacagg ttcgattgaa taaccgtgca tagtattttg
    18241 atacttgtaa aggttggtta tcaacataca gattataaaa aactcataaa ttgctctcat
    18301 acatcatctt gatctgattt caataaataa ctatttagat aacgaaagga gtccttacat
    18361 tatacactat atttggcctc tctccctgcg tgataatcaa aaaattcaca atacagcatg
    18421 tgtgacatat tactgctgca atgagtctaa cgcaacataa taaactccgc actctttata
    18481 attaagcttt aacgataggt ctgggctcat attgttattg atatagtaat gttgtatcaa
    18541 tatcttgcca gatggaatag tgctttggtt gataacacga cttcttaaaa caaaactgat
    18601 ctttaagatt aagtttttta taattgtcat tgctttaatt tgtcgattta aaaatggtga
    18661 tagccttaat ctttgtgtaa aataagagat taggtgtaat aactttaaca tttttgtcta
    18721 gtaagctact attccattca gaatgataaa attaaaagaa aagacatgac tgtaaaatca
    18781 gaaatacctt ctttacaata tagcagacta gataataatc ttcgtgttaa tgataattaa
    18841 ggcattgacc acgctcatca gaaggctcac tagaataaac gttgcaaaaa ggatccctgg
    18901 aaaaatggtc gcacacaaaa atttaaaaat aaatctattt cttctttttt gtgtgtcca
//

